Medical Research Council. Special Report Series No. 259. 'The Murine Type of Tubercle Bacillus (The Vole Acid-Fast Bacillus)'
نویسنده
چکیده
In 1937 Dr. A. Q. Wells discovered an acid-fast bacillus giving rise to a disease in voles which he described as tuberculosis. Though it was regarded by some as a form of leprosy, further investigations showed that his description of the disease was essentially correct. The first part of the present report written by Dr. Wells himself, deals with the morphology, culture and pathogenicity of the vole bacillus and results of immunization experiments with it. The bacillus can be grown in artificial culture and is capable of producing characteristic tuberculous reactions when injected into animals; it is antigenically indistinguishable from the human and bovine types of tubercle bacillus, and it forms a tuberculin in liquid media which is very closely allied to, if not identical with, mammalian ' old tuberculin'. It is therefore fair to conclude that the organism is a third type of mammalian tubercle bacillus, and the term ' murine type of
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